Issued QS-21 patents
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| US Patent No. |
Date Issued |
Coverage |
| 6,645,495 |
Nov. 11, 2003 |
Compositions comprising saponin adjuvants, antigens and excipients |
| 6,524,584 |
Feb. 25, 2003 |
Methods for enhancing an immune response to an antigen using novel combinations of saponin adjuvants |
| 6,231,859 |
May 15, 2001 |
Compositions comprising novel combinations of saponin adjuvants having synergistic immune adjuvant activity at suboptimal doses. Read press release. |
| 5,650,398 |
July 22, 1997 |
Compositions of chemically modified saponins and methods of
use thereof for increasing the systemic uptake of pharmacologically active
substances |
| 5,583,112 |
Dec. 10, 1996 |
Compositions of saponin-antigen covalent conjugates and methods
of use thereof to enhance immune responses |
| 5,443,829 |
Aug. 22, 1995 |
Compositions of chemically modified saponins |
| 5,273,965 |
Dec. 28, 1993 |
Compositions of chemically modified saponins and methods of
use thereof for increasing the uptake of pharmacologically active substances
across mucous membranes |
| 5,057,540 |
Oct. 15, 1991 |
Compositions of saponins purified from
Quillaja saponaria, including QS-21, and methods of use thereof
to enhance immune responses to an antigen |
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