Antigenics to Report Fourth Quarter and Year-End 2007 Financial Results on February 21, 2008; Conference Call to Follow

NEW YORK — Februry 14, 2008 — Antigenics Inc. (NASDAQ: AGEN) will release its fourth quarter and full-year 2007 financial results before the market opens on February 21, 2008.

Antigenics executives will host a conference call at 11:00 a.m. ET that same day. To access the live call, dial 877.762.5772 (domestic) or 706.643.6986 (international); the access code is 35347193. The call will also be webcast and will be accessible from the company’s website at www.antigenics.com/webcast/. A replay will be available approximately two hours after the call through midnight ET on March 6, 2008. The replay number is 800.642.1687 (domestic) or 706.645.9291 (international), and the access code is 35347193. The replay will also be available on the company’s website approximately two hours after the live call.

Antigenics is a biotechnology company developing treatments for cancers and infectious diseases. For more information, please visit www.antigenics.com.