Aroplatin references

2006

Dragovich T, Mendelson D, Kurtin S, Richardson K, Von Hoff D, Hoos A. A Phase 2 trial of the liposomal DACH platinum L-NDDP in patients with therapy-refractory advanced colorectal cancer. Cancer Chemother Pharmacol 2006;58:759-764.

2005

Lu C. Perez-Soler R, Piperdi B et al. Phase II study of a liposome-entrapped cisplatin analog (L-NDDP) administered intrapleurally and pathologic response rates in patients with malignant pleural mesothelioma. J Clin Oncol 2005;23:3495-3501.

2004

Jerremalm E, Hedeland M, Wallin I, Bondesson U, Ehrsson H. Oxaliplatin degradation in the presence of chloride: identification and cytotoxicity of the monochloro monooxalato complex. Pharm Res 2004;21:891-894.

2003

Faivre S, Chan D, Salinas R, Woynarowska B, Woynarowski JM. DNA strand breaks and apoptosis induced by oxaliplatin in cancer cells. Biochem Pharmacol 2003;66:225-237.

2000

Fox LE, Rosenthal RC, King RR et al. Use of cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexane platinum (II), a liposomal cisplatin analogue, in cats with oral squamous cell carcinoma. Am J Vet Res 2000;61:791-795.

MacLean DS, Khokhar AR, Perez-Soler R. Neutron activation of NDDP, a liposomal platinum antitumor agent. Cancer Biother Radiopharm 2000;15:253-259.

MacLean DS, Khokhar AR, Tyle P, Perez-Soler R. Intraliposomal chemical activation patterns of liposomal cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexane platinum (II) (L-NDDP) – a potential antitumour agent. J Microencapsul 2000;17:307-322.

Tardi P, Choice E, Masin D, Redelmeier T, Bally M, Madden TD. Liposomal encapsulation of topotecan enhances anticancer efficacy in murine and human xenograft models. Cancer Res 2000;60:3389-3393.

1999

Drummond DC, Meyer O, Hong K, Kirpotin DB, Papahadjopoulos D. Optimizing liposomes for delivery of chemotherapeutic agents to solid tumors. Pharmacol Rev 1999;51:691-743.

Fox LE, Toshach K, Calderwood-Mays M et al. Evaluation of toxicosis of liposome-encapsulated cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexane platinum (II) in clinically normal cats. Am J Vet Res 1999;60:257-263.

Perez-Soler R, Walsh GL, Swisher SG et al. Phase II study of a liposome-entrapped cisplatin analog (L-NDDP) administered intrapleurally in patients with malignant pleural mesothelioma (MPM). Abstract, ASCO, 1999.

Verschraegen CF, Mansfield P, Feig B et al. Phase I study of an intraperitoneal liposomal cisplatin analog L-NDDP for treatment of peritoneal carcinomatosis. Abstract, ASCO, 1999.

1998

Raymond E, Chaney SG, Taamma A, Cvitkovic E. Oxaliplatin: a review of preclinical and clinical studies. Ann Oncol 1998;9:1053-1071.

Raymond E, Faivre S, Woynarowski JM, Chaney SG. Oxaliplatin: mechanism of action and antineoplastic activity. Semin Oncol 1998;25:4-12.

1997

Perez-Soler R, Shin DM, Siddik ZH et al. Phase I clinical and pharmacological study of liposome-entrapped NDDP administered intrapleurally in patients with malignant pleural effusions. Clin Cancer Res 1997;3:373-379.

Raymond E, Buquet-Fagot C, Djelloul S et al. Antitumor activity of oxaliplatin in combination with 5-fluorouracil and the thymidylate synthase inhibitor AG337 in human colon, breast and ovarian cancers. Anticancer Drugs 1997;8:876-885.

Before 1997

Han I, Khokhar AR, Perez-Soler R. Intraliposomal conversion of lipophilic cis-bis-carboxylato-trans-R,R-1,2-diaminocyclohexane-platinum (II) complexes into cis-bis-dichloro-trans-R,R-1,2-diaminocyclohexane-platinum (II). Cancer Chemother Pharmacol 1996;39:17-24.

Han I, Ling YH, al-Baker S, Khokhar AR, Perez-Soler R. Cellular pharmacology of liposomal cis-bis-neodecanoato-trans-R,R-1,2- diaminocyclohexaneplatinum(II) in A2780/S and A2780/PDD cells. Cancer Res 1993;53:4913-4919.

Han I, Ling YH, Khokhar AR, Perez-Soler R. Cell death and DNA fragmentation induced by liposomal platinum(II) complex, L-NDDP in A2780 and A2780/PDD cells. Anticancer Res 1994;14:421-426.

Han I, Nguyen T, Yang LY, Khokhar AR, Perez-Soler R. Cellular accumulation and DNA damage induced by liposomal cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexane platinum (II) in LoVo and LoVo/PDD cells. Anticancer Drugs 1994;5:64-68.

Khokar AR, al-Baker S, Brown T, Perez-Soler R. Chemical and biological studies on a series of lipid-soluble (trans-(R,R)- and –(S,S)-1,2-diaminocyclohexane) platinum (II) complexes incorporated in liposomes. J Medicinal Chem 1991;34:325-329.

Khokhar AR, al-Baker S, Krakoff IH, Perez-Soler R. Toxicity and antitumor activity of cis-bis-carboxylato(trans-R,R-1,2- diaminocyclohexane) platinum(II) complexes entrapped in liposomes. Cancer Chemother Pharmacol 1989;23:219-224.

Khokhar AR, al-Baker S, Perez-Soler R. Toxicity and efficacy studies on a series of lipid-soluble dineodecanoato(trans-R,R- and trans-S,S-1,2-diaminocyclohexane) platinum (II) complexes entrapped in liposomes. Anticancer Drugs 1992;3:95-100.

Khokhar AR, al-Baker S, Perez-Soler R. Toxicity and anti-tumor activity of hydrophobic diammine and diaminocyclohexane platinum complexes entrapped in multilamellar vesicles. Anticancer Drug Des 1988;3:177-184.

Khokhar AR, Wright K, Siddik ZH, Perez-Soler R. Organ distribution and tumor uptake of liposome entrapped cis-bis-neodecanoato trans-R, R-1,2 diaminocyclohexane platinum (II) administered intravenously and into the proper hepatic artery. Cancer Chemother Pharmacol 1988;22:223-227.

Lautersztain J, Perez-Soler R, Turpin J et al. Cellular pharmacology of liposomal cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexaneplatinum (II) in mouse resident peritoneal macrophages, Kupffer cells, and hepatocytes. Cancer Res 1988;48:1300-1306.

Li S, Khokhar AR, Perez-Soler R, Huang L. Improved antitumor activity of cis-Bis-neodecanoato-trans-R,R-1,2-diaminocyclohexaneplatinum (II) entrapped in long-circulating liposomes. Oncol Res 1995;7:611-617.

Mauldin SK, Gibbons G, Wyrick SD, Chaney SG. Intracellular biotransformation of platinum compounds with the 1,2-diaminocyclohexane carrier ligand in the L1210 cell line. Cancer Res 1988;48:5136-5144.

Mori A, Wu SP, Han I, Khokhar AR, Perez-Soler R, Huang L. In vivo antitumor activity of cis-bis-neodecanoato-trans-R,R-1, 2-diaminocyclohexane platinum(II) formulated in long-circulating liposomes. Cancer Chemother Pharmacol 1996;37:435-444.

Perez-Soler R, Francis K, al-Baker S, Pilkiewicz F, Khokhar AR. Preparation and characterization of liposomes containing a lipophilic cisplatin derivative for clinical use. J Microencapsul 1994;11:41-54.

Perez-Soler R, Han I, Al-Baker S, Khokhar AR. Lipophilic platinum complexes entrapped in liposomes: improved stability and preserved antitumor activity with complexes containing linear alkyl carboxylato leaving groups. Cancer Chemother Pharmacol 1994;33:378-384.

Perez-Soler R, Khokhar, AR. Lipophilic cisplatin analogues entrapped in liposomes: role of intraliposomal drug activation in biological activity. Cancer Res 1992;52:6341-6347.

Perez-Soler R, Khokhar AR, Lautersztain J, Mitchell PA, Schmidt KL. Ultrastructural and freeze fracture localization of multilamellar liposomes containing a lipophilic cisplatin analogue in normal tissues and liver metastases of M5076 reticulosarcoma. Cancer Drug Deliv 1987;4:75-88.

Perez-Soler R, Khokhar AR, Lopez-Berestein G. Treatment and prophylaxis of experimental liver metastases of M5076 reticulosarcoma with cis-Bis-neodecanoato-trans-R,R-1,2-diaminocyclohexaneplatinum (II) encapsulated in multilamellar vesicles. Cancer Res 1987;47:6462-6466.

Perez-Soler R, Lautersztain J, Stephens LC, Wright K, Khokhar AR. Preclinical toxicity and pharmacology of liposome-entrapped cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexane platinum(II). Cancer Chemother Pharmacol 1989;24:1-8.

Perez-Soler R, Lopez-Berestein G, Lautersztain J et al. Phase I clinical and pharmacological study of liposome-entrapped cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexane platinum (II). Cancer Res 1990;50:4254-4259.

Perez-Soler R, Siddik ZH, Kiumars V, Krakoff I, Khokhar A. Pharmacological studies with new liposome-entrapped cisplatin derivatives. In: Platinum & Other Metal Coordination Compounds in Cancer Chemotherapy. Plenum, 1991, 377-389.

Perez-Soler R, Yang LY, Drewinko B, Lauterzstain J, Khokhar AR. Increased cytotoxicity and reversal of resistance to cis-diamminedichloro-platinum(II) with entrapment of cis-Bis-neodecanoato-trans-R,R-1,2-diaminocyclohexaneplatinum (II) in multilamellar lipid vesicles. Cancer Res 1988;48:4509-4512.

Vadiei K, Siddik ZH, Khokhar AR, al-Baker S, Sampedro F, Perez-Soler R. Pharmacokinetics of liposome-entrapped cis-bis-neodecanoato-trans-R,R- 1,2-diaminocyclohexane platinum(II) and cisplatin given i.v. and i.p. in the rat. Cancer Chemother Pharmacol 1992;30:365-369.